IEDB - MHC Class I Binding Prediction Framework

A web-based framework to automate the evaluation of prediction methods by cross-validation was established as described in the manuscript. This framework provides a common interface to train a prediction tool retrieve predictions from it.

The picture above gives a schematic overview of the framework. Each arrow indicates the exchange of messages in http format. The message content has to be in xml format as specified in this xml schema definition.

If you are a tool developer, please consider integrating your prediction method into this framework. Benefits of integration are an automated, transparent side-by-side comparison with other prediction methods, and an automated update of predictions as more data gets available. If you are interested, please contact us, and we will be happy to provide you with support and answer questions.